R&D Focus
We design and develop pharmaceutical drugs targeting the central nervous system (CNS) and the immune system to treat neurological diseases and psychiatric disorders.
-
The Central Nervous System (CNS) is a critical component of the nervous system that consists of two main structures: the brain and the spinal cord. It serves as the control center for processing and transmitting information throughout the body.
1. Components:
- Brain: The brain is the most complex organ and is responsible for cognitive functions, emotions, sensory processing, and coordination of body activities. It has several parts including the cerebrum, cerebellum, and brainstem, each with specific functions.
- Spinal Cord: The spinal cord extends from the brain down the vertebral column and transmits signals between the brain and the rest of the body. It is also responsible for reflex actions.
2. Function:
- The CNS integrates sensory information received from the peripheral nervous system (PNS) and coordinates responses. It controls voluntary movements, regulates involuntary functions (like heartbeat and respiration), and facilitates higher-level functions such as reasoning, memory, and decision-making.
3. Protection:
- The CNS is protected by the skull (for the brain) and the vertebral column (for the spinal cord). Additionally, it is surrounded by three layers of membranes known as meninges, and it is cushioned by cerebrospinal fluid (CSF), which also helps transport nutrients and remove waste.
4. Disorders:
- Various conditions can affect the CNS, including neurodegenerative diseases (like Alzheimer’s and Parkinson’s), multiple sclerosis, traumatic brain injuries, and stroke. These disorders can lead to various neurological deficits, impacting motor skills, cognition, and sensory functions.
5. Development:
- The CNS develops from the embryonic neural tube and continues to evolve throughout life. Neuroplasticity allows the CNS to adapt to new experiences, learn new skills, and recover from injuries to some extent.
Understanding the CNS is critical for fields like medicine, psychology, and neuroscience, as it plays a fundamental role in nearly every aspect of human behavior and physiology.
-
The immune system is a complex network of cells, tissues, and organs that work together to defend the body against infections, diseases, and foreign invaders such as bacteria, viruses, fungi, and parasites. Here’s an overview of its key components and functions:
Key Components of the Immune System:
1. White Blood Cells (Leukocytes):
- Lymphocytes: Includes B cells and T cells. B cells produce antibodies that bind to pathogens, while T cells destroy infected or cancerous cells and help coordinate the immune response.
- Macrophages: Large cells that engulf and digest pathogens and dead cells, playing a crucial role in both the innate and adaptive immune responses.
- Neutrophils: The most abundant type of white blood cells, they are among the first responders to microbial infection.
2. Organs and Tissues:
- Bone Marrow: The primary site for the production of blood cells, including immune cells.
- Thymus: Located behind the sternum, it is where T cells mature and learn to distinguish between self and non-self.
- Spleen: Filters blood and stores white blood cells and platelets, playing a key role in identifying and responding to pathogens.
- Lymph Nodes: Distributed throughout the body, they act as filters for lymph fluid and a site for immune cell activation.
3. Mucosal Immune System:
- Comprising tissues in the mucosal surfaces (like the gastrointestinal tract, respiratory tract, and urogenital tract), it serves as a barrier and provides localized immune responses against external pathogens.
4. Chemical Signals:
- The immune system communicates through cytokines and chemokines, which are signaling molecules that help regulate immune responses.
Functions of the Immune System:
1. Defense Against Pathogens:
- The primary role of the immune system is to identify and eliminate invading microorganisms and viruses.
2. Surveillance:
- The immune system constantly monitors the body for abnormal or cancerous cells, responding to them as necessary.
3. Healing and Recovery:
- It plays a vital role in tissue repair and healing after injury or infection, facilitating recovery processes.
4. Memory:
- The adaptive immune system can "remember" past infections. Upon re-exposure to pathogens, memory cells can mount a faster and more effective response.